| |
|
|
Female |
|
|
Male |
|
| |
Disease |
|
p-valuea |
#Genes b |
p-value |
#Genes |
| a) |
Neurological disease |
|
6.25E-8 - 5.81E-3 |
54(8) |
4.06E-3 - 2.41E-2 |
8(2) |
| |
Rett syndrome |
2.73E-8 |
|
9 |
|
|
|
| |
Psychological disorder |
5.03E-5 |
|
26 |
|
|
|
| |
Mood disorder |
8.94E-5 |
|
20 |
|
|
|
| |
Bipolar affective disorder 7.19E-5 |
|
18 |
|
|
|
|
| |
Taupathy |
1.58E-3 |
|
14 |
|
|
|
| |
Encepahlopathy |
1.79E-5 |
|
10 |
|
|
|
| |
Neuropathy |
2.04E-3 |
|
17 |
|
|
|
| |
Neurodegenerative disease |
2.34E-3 |
|
14 |
|
|
|
| |
Alzheimer’s disease |
3.72E-3 |
|
13 |
|
|
|
| |
Neurological disorder |
5.81E-3 |
|
52 |
2.41E-2 |
8 |
|
| b) |
Infectious disease |
|
9.17E-7 |
|
8(0) |
2.76E-2 |
1(0) |
| c) |
Inflammatory disease/disorder |
|
1.49E-5 - 1.66E-3 |
40(6) |
NSc |
|
| |
Inflammatory bowel disease |
1.42E-4 |
|
20 |
|
|
|
| |
Crohn’s disease |
1.42E-4 |
|
19 |
|
|
|
| |
Arthritis |
4.89E-4 |
|
24 |
|
|
|
| |
Digestive system disorder |
1.47E-3 |
|
20 |
|
|
|
| |
Genetic disorder of heart |
6.69E-5 |
|
3 |
|
|
|
| d) |
Cardiovascular disease |
|
2.25E-5 - 9.47E-03 |
32(3) |
5.58E-3 - 6.45E-2 |
13(9) |
| |
Atherosclerosis |
2.25E-5 |
|
21 |
3.99E-2 |
7 |
|
| |
Thrombosis |
2.26E-4 |
|
5 |
|
|
|
| |
Coronary artery disease |
5.96E-4 |
|
17 |
6.54E-2 |
6 |
|
| |
Cardiovascular disorder |
1.17E-3 |
|
30 |
1.96E-2 |
13 |
|
| |
Myocardial infraction |
|
6.65E-3 |
|
4 |
|
|
| |
Cardiac infraction |
|
9.47E-3 |
|
4 |
3.30E-2 |
1 |
| i) |
Immunological diseases |
|
1.22E-4 - 5.09E-3 |
29(4) |
2.21E-2 |
2(2) |
| |
Rheumatoid arthritis |
|
3.31E-3 |
|
21 |
|
|
| |
Autoimmune disease |
|
5.09E-3 |
|
27 |
|
|
| j) |
Hematopoiesis |
|
2.65E-4 |
|
13(0) |
1.01E-2 |
3(1) |
| k) |
Respiratory disease |
|
3.99E-3 |
|
11(2) |
3.32E-2 |
2(1) |
| l) |
Cancer |
|
5.28E-3 - 1.47E-2 |
19(5) |
3.07E-5 - 3.84E-2 |
14(6) |
| |
Hyperplasia of prostrate |
NS |
|
|
3.07E-5 |
5 |
|
| |
Hyperproliferation |
NS |
|
|
3.29E-2 |
5 |
|
| |
Colorectal cancer |
8.32E-3 |
|
13 |
NS |
|
|
| |
Epithelial ovarian cancer 9.18E-3 |
|
4 |
NS |
|
|
|
| |
Transformation |
1.22E-2 |
|
6 |
NS |
|
|
| m) |
Diabetes mellitus |
8.31E-3 |
|
24(2) |
3.01E-3 |
11(6) |
|
| n) |
Renal and urological disorder |
|
9.47E-3 |
|
10(0) |
5.58E-3 |
1(1) |
| o) |
Organismal injury and abnormalities |
9.47E-3 |
|
9(0) |
5.58E-3 |
3(1) |
| p) |
Connective tissue & muscular disorder |
9.47E-3 |
|
25(1) |
NS |
|
