Figure 3: DU145 phenoxodiol / docetaxel isobologram measured after 48 hr of treatment. DU145 cell proliferation was determined using an MTS assay following 48 hr docetaxel plus phenoxodiol treatment at various doses and combinations. * indicates significant increase in proliferation relative to (0 μM PXD, 100 nM DOC)treatment after 48 hr.