Figure 7: 30 μM PXD and 500 pg/ml sFRP4 protein combination therapy after 48 hr. LNCaP, DU145, and PC3 cell proliferation was determined using an MTS assay following 48 hr 30μM phenoxodiol and 500 pg/ml sFRP4 treatment. * indicates significance relative to DMSO/PBS vehicle control for that time point. ** indicates significance relative to control and * groups for that time point. ***indicates significance relative to control, * and ** groups. ϯ is significance relative to all other treatment groups.