Figure 6: Anti-angiogenesis effects of HL-25 for model mice of HBC after the inoculation of MDA-MB-453 cells (A) Therapeutic effects for model mice of HBC treated with HL-25 on the basis of autopsy analysis. The circles indicate angiogenesis. Scale bar: 10mm. (B) Micrographs of tumor section in model mice of HBC after the treatment with HL-25 using immunostaining of CD34. Scale bar: 10mm. (C) Dimensions of CD34 positive area in tumor of model mice of HBC treated with HL-25 for 14 days. Error bars indicate S.D. (n = 5 per group). Control: 5% glucose solution, DMPC liposomes: 136 mg/kg/day, HL-25: 136 mg/kg/day for DMPC.