GENE Case No. Sex Age (years) Exon Nucleotide Change Amino Acid Change
EGFR 1 M 62 19 742C>A Pro>His
2 M 26 19 742C>A Pro>His
3 M 50 18 691C>A Pro>Thr
4 M 45 19 737A>T Pro>Thr
8 M 65 20 737A>T Lys>Ile
14 F 62 21 742C>A Pro>His
17 M 35 21 742C>A Pro>His
18 F 60 20 737A>T Lys>Ile
22 M 26 21 691C>A Pro>Thr
24 M 45 20 737A>T Lys>Ile
28 M 60 20 737A>T Lys>Ile
34 F 70 21 691C>A Pro>Thr
37 M 65 20 737A>T Lys>Ile
PTEN 1 M 62 5 449G>A D152N
3 M 50 5 449G>A D152N
6 F 65 5 384G>A G128R
10 F 50 7 628A>G T211A
18 F 60 7 628A>G T211A
26 M 58 7 628A>G T211A
30 M 57 5 384G>A G128R
Table 3: Genetic alterations in EGFR and PTEN genes in GBM patients.