First Author Year Country Cancer Genotyping Methods Source of controls Groups R462Q Genotypes Total HWEa Ref.
RR RQ QQ
Barbison 2011 Argentina Cervical Pyrosequencing HB Controls 44 57 22 123 0.64 [22]
            Cases 44 48 6 98    
Beuten 2010 USA Prostate Taqman Assay HB Controls 126 91 7 224 0.05 [24]
            Cases 75 64 17 156    
San Francisco 2014 Chile Prostate Taqman Assay PB Controls 11 6 4 21 0.11 [12]
            Cases 43 31 9 83    
Zabala 2009 Venezuela Prostate PCR-ASA HB Controls 34 16 2 52 0.95 [23]
            Cases 37 10 4 51    
Abbreviation: HB: Hospital Base; PB: Population Based; PCR-ASA: Polymerase-Chain Reaction Allelic Specific Amplification; HWE: Hardy-Weinberg Equilibrium. aThe Hardy-Weinberg Equilibrium was calculated by the 2-test, values greater than 0.05 are consider to agree
Table 1: Characteristics of each study included in the meta-analysis.