Sample A BRCA1 polymorphisms sequencing results Type of mutation Nucleotide Position Mutation Insertion A 185 185insA Insertion T 204 204insT Change C>A 211 211C>A Change A>C 212 212A>C Change G>A 214 214G>A Change T>A 216 216T>A Insertion GTA 219 219insGTA Change A>T 220 226A>T Sample B BRCA2 polymorphisms sequencing results Change A>T 3419 3419A>T Deletion T 3421 3421delT Change A>C 3487 3487A>C

Table 2: Sequencing results on one region of sample A encompassing the exon 11 and sample B which corresponds to BRCA1 and BRCA2 respectively. Here we can detail the sequence variations for BRCA1 and BRCA2, where we found different single nucleotide mutations not previously reported. Only the Sample A 185insA has been reported in the BIC database.