Cell Line Gene Mutations A549 ATR, CBL, CTNNA1, ERC1, FH, FUS, HIP1, KRAS, POLE, STK11, SUFU, TBL1XR1 H2347 AKAP9, ALK, ARID1B, ATRX, BRCA1, CARD11, CLIP1, CUX1, EP300, EWSR1, EZH2, FAM131B, FGFR4, FOXO4, FOXP1, KDR, KMT2C, KRAS, MECOM, MYH9, NBN, NF1, NRAS, NRG1, NSD1, PHOX2B, PMS1, RANBP2, SND1, SS18, TSC1

Table 1: The Catalogue of Somatic Mutations in Cancer (COSMIC) database (cancer.sanger.ac.uk), specifically the Cell Line Project Resource, was analyzed for mutations in the male derived A549 and female derived H2347 cell lines. The following filters were applied: mutation impact: pathogenic and genes: cancer gene census. Table 1 represents the results of this analysis and lists the genes which are implicated in cancer development and have mutations classified as pathogenic in both A549 and H2347 cell lines.