Resisting
Figure 1: 1- Resisting cell death; 2 - Sustaining proliferative signaling; 3 - Evading growth suppressors; 4 - Aktivating invasion and metastasis; 5 - Enabling replicative immortality; 6 - Inducing angiogenesis; 7 - Deregulating cellular energetics; 8 - Evoiding immune destruction; 9 - Development of medicinal resistance; 10 - Tumor promoting inflammation; 11 - Genome instability and mutation; 12 - "RNA world": long non-coding RNA, dsRNA, siRNA, miRNA.