Apoptosis Necrosis Product Dose CBMN Flow cytometry CBMN Flow cytometry Control 0 6.3 ±3.4 1.2 ± 0.3 5.3 ± 1.3 1.7 ± 0.8 Permethrin Low 25.3 ± 3.4 1.0 ± 0.0 40.6 ± 14.31 *3.7 ± 0.4 High 24.7 ± 7.4 *3.6 ± 0.0 *57.3 ± 4.91 *5.4 ± 0.6 Maldison Low 7 ± 1.2 1.1 ± 0.4 *61.3 ± 11.46 0.9 ± 0.3 High *27.6 ± 3.2 1.1 ± 0.4 32.6 ± 4.25 *1.3 ± 0.2 Tee Tree Oil Low 22 ± 12.9 1.3 ± 0.2 14.3 ± 6.36 1.4 ± 0.1 High 23.6 ± 9.6 *6.7 ± 0.2 15.3 ± 2.96 13.3 ± 7 Lavender Oil Low 6.6 ± 1.20 *5.6 ± 1.2 7.6 ± 4.17 6.7 ± 1.7 High 6 ± 3.21 *4.6 ± 1.2 4.3 ± 1.76 *16.3 ± 5 Pyrethrum Low 9.3 ± 5.23 1.4 ± 0.6 18 ± 6.66 2.3 ± 0.3 High 9.6 ± 5.24 *6.5 ± 0.6 11 ± 1.52 *4.4 ± 0.4

Table 2: Cell killing mechanism of head lice treatments determined by CBMN and the Flow cytometry based apoptosis/necrosis assay. Dose code from Table 1.