Figure 1: MRI images demonstrating GBM therapy resistance to the current available treatment approach. Pre- and post-surgery MRI images, as well as an MRI following standard chemo and radiotherapy treatment in a patient with GBM are shown. Maximal surgical resection of the tumor mass removes all visible tumor-related tissue. Despite extensive chemotherapy and radiotherapy, a follow-up MRI several months later reveals the tumor mass has returned to its original location. Tumor recurrence occurs in virtually all GBM patients.