Upstream Regulator Molecule Type p-value of overlap Target molecules in dataset
CTCF transcription regulator 1.43E-08 MUC2,MUC5B,MUC6
IL22 cytokine 4.90E-08 MUC1,MUC4,MUC5B
GAB2 other 1.77E-06 MUC2,MUC5B
IL1B cytokine 2.06E-04 MUC1,MUC3A,MUC4
TSC2 other 7.93E-04 MUC2
FOXA1 transcription regulator 7.93E-04 MUC4
AGR2 other 1.59E-03 MUC1
DDIT4 other 1.59E-03 MUC2
CDX1 transcription regulator 1.59E-03 MUC4
SP1 transcription regulator 2.58E-03 MUC2,MUC5B
NFATC3 transcription regulator 3.17E-03 MUC2
RPS6KB1 kinase 3.17E-03 MUC1
Secretase gamma complex 3.96E-03 MUC2
DNMT3A enzyme 3.96E-03 MUC4
HNF1B transcription regulator 3.96E-03 MUC4
SIM2 transcription regulator 4.75E-03 MUC2
ATF1 transcription regulator 6.33E-03 MUC5B
miR-145-5p (and other miRNAs w/seed UCCAGUU) mature microRNA 7.12E-03 MUC1
ERBB2 kinase 7.12E-03 MUC1
IL13 cytokine 8.66E-03 MUC2,MUC5B
MTOR kinase 9.48E-03 MUC1
HDAC3 transcription regulator 9.48E-03 MUC4
PRKCD kinase 1.26E-02 MUC5B
HNF4A transcription regulator 1.26E-02 MUC4
Akt group 1.50E-02 MUC1
CAMP other 1.81E-02 MUC2
CDX2 transcription regulator 2.82E-02 MUC4
GATA4 transcription regulator 2.90E-02 MUC4
HDAC1 transcription regulator 2.90E-02 MUC4
SP3 transcription regulator 3.28E-02 MUC2
HIF1A transcription regulator 3.67E-02 MUC1
TLR2 transmembrane receptor 3.89E-02 MUC2
ERK group 4.28E-02 MUC8
DNMT3B enzyme 4.35E-02 MUC4
Histone h3 group 4.73E-02 MUC4
Table 3: Upstream regulators for mucin genes.