| |
Molecule |
Core protein size (kDa) |
GAG type (number of GAGs) |
| SLRPs |
Decorin |
40 |
CS/DS (1) |
| Biglycan |
40 |
CS/DS (1-2) |
| Asporin |
43 |
none |
| Fibromodulin |
58 |
KS (4) |
| Lumican |
38 |
KS (2-3) |
| Modular PGs |
Versican (isoforms V0- V4) |
370, 262, 180, 72, 115 (V0-V4) |
CS/DS (0-23) |
| |
Aggrecan |
210-250 |
CS (100) KS (30) |
| Brevican |
50,80,145 |
CS (0-5) |
| Perlecan |
400-467 |
HS (3-10)/(CS, DS, hybrid
HS/CS, CS/DS chains or
GAG-free glycoprotein) |
| HA* |
Very low, low, medium
and high HA species |
Molecular weight (kDa)
50, 300, 800, 2000-3000 |
Repeating glucuronic acid and
N-acetylglucosamine
disaccharides |
*HA is the only GAG synthesized in a free form lacking a protein core. |
