Figure 4: Mc1r function influences repair of UV-induced DNA damage. Mc1r-intact (Mc1rE/E) or –defective (Mc1re/e) mice were exposed to UV. Clearance of thymine dimers in the skin was followed over time by Southwestern analysis using a monoclonal antibody against thymine dimers. Note that animals with intact Mc1r cleared thymine dimers more efficiently than Mc1r-defective mice.