Figure 4: A: Putative collective epiblast cell movement during gastrulation according to Chuai et al. [43]. B: Schematic drawing of dispersal of mutated cells in multiple and unilateral BFHs in BLs without extracutaneous anomalies. C: Schematic drawing of dispersal of mutated cells in Happle-Tinschert syndrome with midline crossing of mutated cells. D: Schematic drawing of dispersal of mutated cells in Happle-Tinschert syndrome with mutated cells on both sides of the epiblast.