Intervention Drugs Condition Sponsor Patients enrolled Phase Period Clinical trial number
Vorinostat (SAHA), Cisplatin, Radiation Stage III or IV of SCC of the oropharynx Ohio University Comprehensive Cancer Center 38 I 2010 2013 NCT01064921  
Capecitabine (Xeloda), Vorinostat (SAHA) Recurrent and/or metastatic head and neck cancer, Nasopharyngeal carcinoma, stage III and IV HNSSC and verrucous carcinoma National (NCI) Cancer Institute 1445 II 2010 2013 NCT01267240
CUDC-101 Cisplatin, Radiation Head and neck cancer Curis, Inc. 22 I 2011 2013 NCT01384799
Valproic acid, Patinum and Radiation Locally advanced head and neck SCC (oral cavity and oropharynx) Intituto do Cancer do Estado de São Paulo 40 II 2012 2014 NCT01695122
SCC: Squamous Cell Carcinoma; HNSCC: Head and Neck Squamous Cell Carcinoma
Table 2: Clinical trials involving HDACi and head and neck squamous cell carcinoma.