Figure 1: PM inhibits proliferation of prostate cancer cells. (A) 1 × 104 LNCaP or PC-3 cells were seeded in each well of a 96-well plate. Twenty-four hours later, cells were treated with PM at concentrations ranging from 0 to 10 μM for 72 h in triplicate. Cell viability was measured by MTS assay using CellTiter AQueous Assay System. *p<0.05 compared to control cells. (B) Morphological changes in cell cultures visualized by light microscopy 48 h after treatment with PM. Each experiment was repeated three times. |