Figure 2: Biopsies treated with anti-Human p53 (Mab) in immunohistochemistry aimed at demonstrating the expression levels of p53 in 4 BPH and 4 PCa biopsies. S38 represents the control having moderate positivity around the basement membrane. This can be likened to p53 expression in regular cell division and is therefore tagged (-/+). In PCa biopsies, p53 expression was immunopositive (+) while it is highly immunonegative in BPH (-). Although few cells scattered at wide intervals showed the cytoplasmic inclusions. The biopsy tagged S29, although diagnosed as BPH, showed high expression levels of p53 similar to that observed in clinically diagnosed PCa biopsies (S29/+).