Figure 6: K-ras Mutation and Expression of vWF and TF. (A) The angiogenic switch occurred as the lesions progressed in size and as expression of vWF increased. WT expressed little vWF. (B) As the lesions progressed in size and vascularity, the expression of TF also increased. (C) K-ras mutation correlated with increased TF expression and increased vascularity (R2=0.9579).