Figure 2: Subcutaneous administration of ODSH (25 mg/kg every 12 h; Days 1-2 and 17.5 mg/kg every 12 h; Days 3-7) had no effect on 30-day survival after whole-body ionizing irradiation alone (RI) but increased mortality when combined with skin burn injury (CI) in female B6D2F1/J mice (D). Survival analysis for control mice (A), RI mice (B) and CI mice (C). N=20-22 per group. Vehicle and ODSH groups received additional topical gentamicin (0.1% cream; Days 1-10) and oral levofloxacin (100 mg/kg; Days 3-16) treatment. Data are expressed as mean values; *p<0.05 compared to vehicle treatment only.