Differential diagnosis of hepatic lesions CT-radiographic finding and contrast enhancement
Metastases Hypodense lesion, asymmetrical contrast enhancement in arterial phase
Hepatocellular carcinoma Hypervascular lesion in arterial phase, whereby the lesion shows a contrast washout in the portal venous phase
Cholangiocellular carcinoma Delayed contrast enhancement
Lymphoma Primary hepatic lymphoma: Either low density lesion in both contrast-enhanced and non-contrast-enhanced CT-scan or bearing a contrast-enhancing rim Secondary hepatic lymphoma: Blood vessel floating sign and enhancement
Subcentimeter focal lesions Difficult to charakterize by radiographics, whereas over 80 % are benign
Haemangioma Arterial hyper-enhancement in all phases or globular, peripheral or discontinuous enhancement in portal venous phase
Focal steatosis Nodular appearance, hypodense lesion due to fatty infiltration
Cysts Hypodense lesions with no contrast enhancement
Focal nodular hyperplasia Iso- / hypodens lesion with contrast enhancement in the arterial phase, persistent hypervascularisation in portal venous phase and central scar
Hepatocellular adenoma Hypodens lesion with hyperdens intersets, hyperdens and often inhomogen in the arterial phase, in portal venous phase iso- / hypodens
Hepatic abscess Depending mainly on the cause. Pyogenic abscesses are well-defined hypodense lesions with rim enhancement
Biliar hamartoma Contrast-enhancement of the stromal components of the tumor
Haemangioendothelioma Hypodense mass in unenhanced CT-scan, resemble contrast-enhancement of haemangioma
Table 2: Differential diagnosis of liver metastases originating from colorectal carcinomas in CT-scan potential intrahepatic lesions [5,9-14].