Figure 7:Elevated serum PSA level in the mice intra-tibially injected with the METCAM/MUC18-expressing-LNCaP and C4-2B clones [50]. 2 × 105 cells from each LNCaP and C42-B clones were injected into one tibial bone of each of male nude mice. Serum PSA levels in the mice were determined by ELISA assays 8 weeks after intratibial injection of METCAM/MUC18-expressing LNCaP (LNLCMC) and C4-2B (C4-2B-MC) clones/cells. LNLC-V and C4-2B-V clones/cells represented the empty vector-transfected cells