Cell line |
Level of human METCAM/MUC18
expression |
Tumor take,
Number of mice with tumor (%)* |
Tumor size (g), mean value (±standard deviation) |
Number of mice with metastatic lesions to (target organs) |
LNCaP (p40) |
none |
2/6 (33%) |
1.85 (±1.77) |
0/6 (none) |
LN-2-6 (p49) |
++++ |
3/9 (33%) |
1.5 (±1.32) |
3/9 (peri-aortic lymph nodes, ureter, kidney, seminal vesicles) |
LN-2-6 (p64) |
+ |
1/5 (20%) |
3 |
1/5 (peri-aortic lymph nodes, ureter, kidney, seminal vesicles) |
LN-2-39 (p57) |
++++ |
3/5 (60%) |
2.57 (±2.45) |
3/5 (peri-aortic lymph nodes, ureter, kidney, seminal vesicles) |
LN-3-5 (p58) |
++++ |
3/4 (75%) |
1.8 (±2.7) |
3/4 (peri-aortic lymph nodes, ureter, kidney, seminal vesicles) |
LN-4-1 (p55) |
none |
1/5 (20%) |
0.7 |
0/5 (none) |
LN-5-1 (p57) |
none |
1/5 (20%) |
8.6 |
0/5 (none) |
|