Clones METCAM/MUC18 Expression Serum PSA level (fold) Number of mice positive (%)
LNCaP#25 (LNLC-MC) Yes 1.24 ± 0.36 ng/ml (2.88) 7/7 (100)
LNCaP-Vector (LNLC-V) No 0.43 ± 0.49 ng/ml (1) 2/5 (40)
C4-2B#31
(C4-2B-MC)
Yes 6.2 ± 9.2 ng/ml (14.4) 6/10 (60)
C4-2B-Vector (C4-2B-V) No 0.43 ± 0.32 ng/ml (1) 2/6 (30)
Table 2: Bone colony formation of huMETCAM/MUC18-expressing LNCaP and C4-2B clones and vector control clones after intra-tibial injection [50].