| |
Ambroxol HCl |
Ambroxol HCl degradate |
Guaifenesin |
Guaicol |
| Validation parameters |
PLS |
PCR |
PLS |
PCR |
PLS |
PCR |
PLS |
PCR |
| (a) Predicted vs. known concentration |
|
|
|
|
|
|
|
| 1- Slope |
0.9795 |
0.9846 |
1.0282 |
1.0276 |
0.9935 |
1.0029 |
0.8840 |
0.9064 |
| 2- Intercept |
0.1793 |
0.1374 |
-0.0917 |
-0.0886 |
0.4375 |
-0.0034 |
1.1865 |
0.9861 |
| 3- Correlation coefficient (r) |
0.9988 |
0.9989 |
0.9991 |
0.9988 |
0.9987 |
0.9980 |
0.9988 |
0.9994 |
| (b) Residual vs. actual concentration |
0.141 |
0.144 |
0.123 |
0.127 |
1.005 |
1.184 |
0.497 |
0.525 |
| ± error in prediction |
|
|
|
|
|
|
|
|
| (c) RMSEP |
0.031 |
0.025 |
0.019 |
0.020 |
0.251 |
0.117 |
0.085 |
0.095 |
|
