Compound

Concentration of
    LOQ Solution in %
  (With respect to sample Concentration)

Signal
to noise ratio

Impurity-1

0.03

10.9

Impurity-2

0.03

12.2

Bortezomib

0.02

10.6

Impurity-3

0.03

14.1

Impurity-4

0.03

13.1

Impurity-5

0.03

11.9