Compound

USP Resolution (RS )

USP Tailing
factor

No. of theoretical plates (USP tangent method)

Impurity-1

--

1.2

19262

Impurity-2

8.4

1.3

26407

Bortezomib

5.9

1.3

14667

Impurity-3

2.2

1.3

25578

Impurity-4

2.7

1.2

62743

Impurity-5

3.8

1.2

71445