Lot No.

Imp-1

Imp-2

Imp-3

Imp-4

Imp-5

Max. Single Unknown Imp.

Total impurities

Assay by HPLC

001

0.01

ND

0.04

0.06

0.01

0.04

0.17

99.9

002

0.02

ND

0.06

0.08

0.02

0.03

020

99.8

003

0.01

ND

0.04

0.07

0.02

0.01

0.17

99.7

Figure 4: Linearity chart for bortezomib impurities.