Parameters TLC- Densitometric Method Reported Method [26 ] EZ AT EZ AT Atoreza ®a (B.N. 1031061)   101.05± 1.302 99.86± 1.695 101.93± 0.749   99.78± 1.049 Standarad Additionb   100.52± 1.810 100.26± 2.072     F-test c   3.022 (9.272) 2.584 (6.591)     Student's t-test c   1.165 (2.446) 0.125 (2.364)     aAverage of 5 determinations. bAverage of 3determinations. cThe values in the parenthesis are corresponding theoretical value at p= 0.05.[degree of freedom in dosage form =6 for EZ and 7 for AT]. [26] Spectrophotometric determination of EZ and ATR using 1DD at 289.5 and 288 nm for EZ and AT, respectively and methanol as solvent.

Table 2: Determination of the EZ and AT in Atoreza® tablets by the proposed method and statistical comparison with the reported method.