Stress condition        % Assay      % Net degradation
6N Hydrochloric acid/Reflux 1 Hrs 95.4 4.6
6N Sodium hydroxide/Reflux 1 Hrs 94.7 5.3
6N Hydrogen peroxide/Reflux 1 Hrs 98.2 1.8
Water/Reflux 1 Hrs 99.0 1.0
90% Humidity/7 Days 99.5 0.5
Thermal 105°C/8 Hrs 99.3 0.7
UV light 99.2 0.8
Peak purity was passed for ibuprofen and paracetamol peak for all type of stressed samples.
Table 7: Selectivity & Specificity.