Parameter Proposed
method
Official
Method [1]
% Founda 102.00 99.16
99.40 100.32
100.00 99.48
99.48 100.15
100.64  
99.33  
Mean ± S.D. 100.14 ± 1.04 99.78 ± 0.55
t 0.64 (2.31)b
F 3.568 (9.013)
aThe average of three separate determinations.
bThe figures between parentheses are the tabulated values of t and F at P=0.05.
Table 8: Assay results for the determination of atenolol in pure form by the HPLC and official methods.