% RSD

Parameters Lisinopril Enalapril Captopril Fosinopril
Retention time (Rt. In minutes) 0.006 0.003 0.021 0.025
Capacity factors (K’) 0.0000 0.0000 0.009 0.0090
Theoretical plates (N) 0.3661 0.0527 0.2551 0.008
Tailing factor (T) 1.311 1.1778 0.1127 0.0454
Resolution (R) 0.1023 0.0000 0.1220 0.1000
LLOD (Bulk material) ngmL-1 0.007 0.102 0.050 0.00
LLOD (Serum) ngmL-1 0.0325 0.0790 0.1294 0.010
Table 1: System suitability parameters sensitivity of the proposed method.