Parameters Spectrophotometric method HPLC method PE LC TM PE LC TM Calibration range 5-50 μgmL-1 5-70 μgmL-1 5-40 μgmL-1 5-55 μgmL-1 5-70 μgmL-1 5-60 μgmL-1 Slope 5.0306 2.0664 1.4087 0.5861 1.1924 0.7678 Intercept -0.0862 3.5372 -1.2562 -0.4193 0.3133 -0.2720 Correlation  coefficient(r) 0.9999 0.9999 0.9998 0.9999 0.9999 0.9998 Accuracy 100.25 99.67 100.53 99.85 99.78 99.53 Precision     Repeatability 1.635 0.340 1.027 1.037 1.382 1.188 Intermediate precision 0.582 0.548 0.348 0.680 0.627 0.870

Table 2: Regression and analytical parameters of the proposed methods for determination of Lidocaine, Phenylepherine and Thiomersal.