Drug Proposed CZE method Reference method       Ref. [2]
    NLB Taken µg mL-1 Found µg mL-1 % Recovery Taken µg mL-1 Found µg mL-1 % Recovery
5
50
100
140
160
200		 4.99
49.85
98.88
139.47
159.53
199.74		 99.80
99.70
98.88
99.62
99.70
99.87		 2
4
6
8
10
15		 1.99
3.98
5.87
8.00
9.99
14.88		 99.50
99.50
97.83
100.00
99.90
99.20
Mean ± SD
n
Variance
**%SE
t-test
F-test		 99.60 ± 0.4
6
0.16
0.16
0.845(2.228)*
3.06(5.05)*		 99.32 ± 0.7
6
0.49
0.29
    NLX 20
60
100
140
160
180		 19.77
59.28
98.65
139.47
158.98
179.85		 98.85
98.80
98.65
99.99
99.36
99.92		 10
20
40
60
80
100		 10.00
19.99
39.85
59.78
79.63
98.85		 100.00
99.95
99.62
99.63
99.53
98.85		     Ref [10]
Mean ± SD
n
Variance
**%SE
t-test
F-test		 99.26 ± 0.6
6
0.36
0.24
1.144(2.228)*
2.25(5.05)*		 99.59 ± 0.4
6
0.16
0.16
    NLT 10
50
80
100
150
200		 10.00
49.58
79.89
99.85
149.57
199.74		 100.00
99.16
99.86
99.85
99.71
99.87		 12
16
20
24
28
32		 11.95
15.99
19.68
23.98
28.00
31.67		 99.58
99.93
98.40
99.92
100.00
98.97		     Ref [21]
Mean ± SD
n
Variance
**%SE
t-test
F-test		 99.74 ± 0.3
6
0.09
0.12
1.006(2.228)*
4.00(5.05)*		 99.47 ± 0.6
6
0.36
0.24
*Figures in parentheses are the tabulated values of t-and F- testes at 95% confidence limit [32]; **%SE= SD /image
Table 2: Analytical results of the determination of NLB, NLX and NLT in bulk powder using CZE method and reference methods.