Figure 1: A) Transverse section of duodenum from control rats: showing the villi covered with two cell types: a single layer of columnar epithelial cells (enterocytes) (arrows) and goblet cells (head arrows). H&E,X1000. B-E) Transverse sections of duodenum from soriatane treated rats: (b) showed decrease in number of villi, fusion of villi ( arrow), atrophy (head arrow),.H&E,X400. (c) villi stunting (arrows).H&E.X400. (d) edematous (o) of the lamina propria. H&E. X1000. (e) flattening of the epithelial cells with villus core inflammation and villi distortion. H&E. X 1000.