CG ICS21 p Total area spleen (105 µm) 9.88 ± 2.09 9.61 ± 1.39 0.92a Area of white pulp of the spleen (104 µm) 4.65 ± 1.33 3.16 ± 0.52 0.41b Area of red pulp of the spleen (106 µm) 0.99 ± 0.24 1.08 ± 0.13 0.82b Thickness trabecula (101 µm) 3.86 ± 0.40 3.28 ± 0.22 0.37b

Table 2: Measurements of the total areas, white pulp, red pulp and splenic trabecular thickness. Results are presented as mean ± SEM. CG: control group; ICS21: inhalation cigarette smoke during pregnancy (21 days); N=7 per group. a Student's t-test; b Mann–Whitney U test.