Figure 2: CD68+ immunohistochemistry in the germinal epithelium of wild type adult Sprague-Dawley rats. (A) Control (B) 100mg/Kg Pb-Acetate (C) Pb-Acetate+Se+Zn and (D) Se+Zn only. CD68 activity is higher around the BM of the epithelium where the cell population is basically composed of spermatogonia and the sustenacular cells of Sertoli; (‡) represents regions of CD68 immunopositivity and (†) represents regions of cellular degeneration, (n) represents normal cells of the epithelium, (BM) basement membrane, arrow head indicates the lumen of the seminiferous tubule (Scale bar is 30μm).