Figure 3: CD20+ immunohistochemistry in the germinal epithelium of wild type adult Sprague-Dawley rats. (A) Control (B) 100 mg/Kg Pb-Acetate (C) Pb- Acetate+Sn+Zn and (D) Se+Zn only. CD20+ activity is higher around the BM and the Sertoli cell region of the epithelium where (‡) represents regions of CD68 immunopositivity and (†) represents regions of cellular degeneration, (n) represents normal cells of the epithelium, (BM) basement membrane, arrow head indicates the lumen of the seminiferous tubule. Se+Zn (3D) showed a widely diffused CD20+ reaction (Scale bar is 30 μm).