Animal Group
(n=6) |
Initial Body Weight (gm) |
Final Body Weight (gm) |
Change in Body weight |
Kidney weight (gm) |
(kidney/Body Weight Ratio)
X 1000 |
| Mean ± SD |
Mean ± SD |
gm (±) |
% (±) |
Mean ± SD |
Mean ± SD |
| Control |
186.3 ± 4.6 |
205.3 ± 5.8a |
(+)19±2.8 |
(+)10.2% |
0.8 ±0.01 |
3.9 ± 0.0003 |
| Cisplatin |
191.0 ± 4.7 |
183.8 ± 4.3ab |
(-) 7.5±0.8 |
(-) 3.9% |
0.72 ±0.014d |
4.2 ± 0.0002e |
| Misoprostol |
184.3 ± 4.8 |
193.83 ± 7.11abc |
(+) 9.5±3.1 |
(+) 5.2% |
0.74 ± 0.014d |
3.8 ± 0.0012 |
| MP + CP |
185.8 ± 4.9 |
186.50 ± 5.6b |
(+) 0.8±1.9 |
(+) 0.43% |
0.76 ± 0.012d |
4.0 ± 0.0002e |
All data are expressed as Mean ± SD, n=6. a: where P <0.001 of initial vs. final BW of same group; b: P <0.001 vs. final BW of controls; c: P<0.001 vs. final BW of cisplatintreated
group; d: Significantly different of kidney weight at P.< 0.005) vs. control; e: Significantly different in kidney weight/body weight ratio vs. normal control group at P.
< 0.005. (+) increase. (-): decrease. |
