Animal group
(n=6)
Serum Creatinine (mg/dl) BUN (mg/dl)
Mean ± SD Mean ± SD
Control 0.96 ± 0.08 22.3 ±3.37
Cisplatin 2.11 ± 0.11a 58.03 ± 3.27a
Misoprostol 0.95 ± 0.042b 24.4 ± 3.36b
Misoprostol + Cisplatin 1.46 ± 0.12ab 47.39 ± 4.5ab
All data are expressed as Mean ± SD, n=6. a: Significantly different Vs. control group at P <0.001.b: Significantly different Vs. cisplatin-treated group at P. <0.001
Table 2: Effect of cisplatin and/or misoprostol on serum creatinine and BUN (mg/ dl) in Rat.