Figure 4: SiRNA mediated downregulation Wnt-β-catenin pathway blocked VM in TNBC cells A: MDA-MB231 TNBC cell line, was transiently transfected with beta-catenin SiRNA for three different time points (48-96 hours) and beta-catenin protein was determined by Western blot B: Genetic attenuation of beta-catenin in MDA-MB231blocked VM over 6 hours. Bars represent mean number of semi-quantified vessels counted per randomly chosen field, *P<0.001 (n= 10) C: Schematics of WP are represented with the tools used in the study.