Figure 1: Intraparenchymal isolated bile ductules (IIBDs). (a) Scattered IIBDs (arrows) distant from a portal area (P), and a highpower view (inset) showing a small bile tubule composed of cuboidal cholangiocytes. (b) A tangential IIBD (arrow) with dilated sinusoidal spaces, and a high-power view (inset) showing its cytokeratin 7 expression. (c) A fibrously expanded portal area (P) and regenerative nodule-like lobule containing an IIBD (arrow), and a high-power view (inset) showing longitudinal features of IIBD