Score Findings
0 Absent or rare single CK7+ cholangiocytes or ductular reaction
1 Rare single or focal ductular reaction or focal clustering of CK7+ cholangiocytes* in periportal areas
2 Continuous ductular reaction or clusters of CK7+ cholangiocytes* occupying <50% of portal areas
3 Continuous ductular reaction or clusters of CK7+ cholangiocytes* occupying >50% of portal areas
CK7: cytokeratin 7
*CK7+ cholangiocytes with and without ductular structures
Table 1: Semi-quantitative assessment of ductular reaction