Figures 1A-1F: shows the immunohistochemical detection of DTdiaphorase in superficial spreading (epidermal invasion) malignant melanomas of the skin: Figure 1A: very strong expression of DTdiaphorase in malignant melanoma cells clusters in epidermis (E). Dermis (D) is not invaded (red line dividing epidermis from dermis). Figure 1B: negatif control of Figure 1A (HE staining). Figures 1C-D: cancer cells clusters (arrows) in epidermis (E). Higher magnifications of Figure1A. Figure 1E-F: another sample showing the very strong expression of DT-diaphorase in superficial spreading malignant melanoma cells invading the epidermis (E) but not the dermis (D). (Figure E, low magnification; figure F, high magnification).