Cx 26 Cx 43 Donor 1, 76 years of age 187 149 Donor 2, 80 years of age 317 199 Donor 3, 81 years of age 139 484 Donor 4, 79 years of age 214 140

Table 1: Summary of the difference of connexin (Cx) density in the inner epidermis between the acupuncture point (AP) Lu11 and its surrounding region in %, separated for different donors and Cxs. Note that all samples show an increase in Cx density within the AP region for both Cxs listed. Measuring formula: intensity of AP x 100 / intensity of surrounding region; an increase is defined by numbers over 100, a decrease by numbers below 100.