Marker % Positivity (Baseline) % Positivity (Post-diet) RFI (Baseline) RFI (Post-diet) Functional description
CD14 99.25 ± 0.228 97.87 ± 0.516
(P=0.0083)
490.75 ± 10.063 428.91 ± 16.192
(P=0.0128)
Monocyte differentiation/maturation antigen
CD18a 99.99 ± 0.008 99.93 ± 0.058
(P=ns)
628.25 ± 10.446 638.25 ± 14.631
(P=ns)
b chain of the leukocyte integrin complexes CD11a/CD18 (LFA-1) [ligand for ICAM-1, ICAM-2, ICAM-3 on endothelial cells] and CD11b/CD18 (Mac-1) [ligand for ICAM-1 on endothelial cells]
CD11a 99.83 ± 0.036 99.43 ± 0.385
(P=ns)
412.41 ± 7.200 390.16 ± 8.324
(P=ns)
a chain of the leukocyte integrin complex LFA-1
CD11R3 98.98 ± 0.210 99.01 ± 0.229
(P=ns)
323.33 ± 13.803 350.00 ± 17.025
(P=ns)
a chain of the leukocyte integrin complex Mac-1, equivalent to human CD11b
CD49d 99.09 ± 0.189 99.09 ± 0.217
(P=ns)
323.50 ± 6.136 305.33 ± 5.829
(P=ns)
a chain of the leukocyte integrin complex CD49d/CD29 (VLA-4) [ligand for VCAM-1 on endothelial cells]
CD29 99.96 ± 0.013 99.93 ± 0.016
(P=ns)
674.33 ± 12.393 674.75 ± 24.605
(P=ns)
b chain of the leukocyte integrin complex VLA-4
CD16 99.98 ± 0.010 99.96 ± 0.018
(P=ns)
585.16 ± 17.155 595.25 ± 14.180
(P=ns)
FcgRIII, low affinity receptor for IgG
CD163 99.94 ± 0.031 99.20 ± 0.475
(P=ns)
581.27 ± 42.086 605.45 ± 33.004
(P=ns)
Haptoglobin scavenger receptor
SLA-DR 48.26 ± 2.336 62.06 ± 5.432
(P=0.0379)
249.75 ± 14.156 284.41 ± 20.086
(P=ns)
Monocyte activation marker, equivalent to human HLA-DR
HCD, hypercholesterolemic diet;SEM, standard error of the mean;ns, not significant
Table 3: Cumulative quantitative variations (Mean ± SEM) of surface markers expression (as percentage of positivity and RFI) in the 6 HCD-treated pigs. Functional description of the markers is reported.