Marker Results
CD20 Positive in follicles and interfollicularatypical large cells
CD79a Positive in follicles and interfollicularatypical large cells
BCL2 Positive in follicles and interfollicularatypical large cells; positive in paracortical and interfolliculat T-cells
PAX5 Positive in follicles and interfollicularatypical large cells
OCT2 Positive in follicles and interfollicularatypical large cells
HGAL Weakly positive in follicles and interfollicularatypical large cells
CD10 Negative with appropriate internal control
BCL6 Negative with appropriate internal control
LMO2 Negative with appropriate internal control
CD3 Positive in paracortical and interfollicular small T-cells
CD5 Positive in paracortical and interfollicular small T-cells
CD21 Positive in follicular dendritic cells; highlights FDC meshworks in most follicles and only focal disruption in few follicles
CD68 Positive in interfollicularhistiocytic cells and highlights increased numbers
CD30 Negative with appropriate internal control
CD15 Negative with appropriate internal control
ALK1 Negative with appropriate external control
EMA Negative with appropriate internal control
PD-1 Negative with appropriate internal control
HHV8 Negative with appropriate external control
Table 1: Immunohistologic profile of transformed follicular lymphoma.