Figure 2: (A and B) Various mutant or wild type Mdm2 expressing MEFs were exposed to Etoposide (A) or H2O2 (B). Apoptotic marker (cleaved PARP) were detected by immunoblotting using anti-PARP antibody (Top), and band intensities were used to assess the level of Cleaved PARP relative to those of full length PARP in each sample (Bottom).