Figure 3: A and B Photomicrographs of ethanol-treated liver sections showed disturbed architecture of hepatocytes plates around central vein (C) and portal tract (P) which showed inflammatory cells infiltration (transparent arrow) encroaching portal vein (v). Degenerating hepatocytes showed cytomegaly, fatty changes and vacuoles (u) while apoptotic cells were numerous and shrunken (dark arrows) with pyknotic nuclei. (400X, Hx&E). C and D Photomicrographs of ethanol-treated liver sections showed degenerating hepatocytes with fatty changes vacuoles (u) and eosinophilic alcoholic hyaline Mallory bodies (arrowheads) which appeared condensed with basophilic disintegrating cytoplasmic content (double arrowheads) in some other cells. Hepatic blood sinusoids were not apparent between the vacuolated hepatocytes and the disfigured architecture. Apoptotic cells were shrunken and numerous (arrows) with pyknosis and karyorrhexis of nuclei (double arrows). (1000X, oil immersion, Hx&E).