Group n   PITX2     LEF-1     β-catenin  
    +(%) c2 P-value +(%) c2 P-value +(%) c2 P-value
Total 42                  
Age                    
<50 20 16(80) 0.019 0.890 14(70) 0.287 0.592 16(80) 0.322 0.057
>50 22 19(86.36)     18(81.82)     20(90.91)    
Grade                    
G1-G2 13 8(61.54) 4.367 0.037 7(53.85) 5.182 0.023 8(61.54) 4.355 0.012
G3 29 27(93.1)     25(86.21)     28(96.55)    
Stage                    
I + II 15 9(60) 6.720 0.01 8(53.33) 4.903 0.027 10(66.67) 4.706 0.03
III + IV 27 26(96.3)     24(88.89)     26(96.3)    
Lymph node metastasis                    
with 26 25(96.15) 5.836 0.016 23(88.46) 4.029 0.045 25(96.15) 4.043 0.044
without 16 10(62.5)     9(56.25)     11(68.75)    
Table 3: Relations between abnormal expressions of PITX2, LEF-1, β-catenin proteins and clinical pathological features of epithelial ovarian cancer.